Peyton Manning and the Broncos relationship disolves and Peyton and Broncos agree to trade Peyton for Kaepernick (Tebow 3.0). Colts trade #1 pick to the niners for Alex Smith. Peyton breaks his neck first week of the season and Josh Johnson starts throwing balls to Trent Richardson who Harbaugh converted to a WR. Okay done talking out of my ass.
Most of the listed selections aren't exactly "oh wow" moments. They generally all have rumors surrounding the pick. Personally I think two truly surprising moves that I could see happening based on historical reaches and players in this current draft (similar reaches to the Locker/Ponder pick from last year and Tyson Aluau from the previous year):
Jaguars select Rueben Randle in the top ten
Browns select Kirk Cousins with their second first round pick
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