To a degree, yes. We are going into this draft needing a QB, a change of pace RB, and a true WCO fullback. I believe Harbaugh knows what he's looking for in terms of those positions, so I expect us to do well in that department(although I'd prefer it if the QB talent pool wasn't littered with question marks).
Our first pick is likely to be on defense, and I don't know how much input Harbaugh will have on that. The teams that Fangio was DC for don't blow me away as far as their defensive picks during his tenure. Houston took Dunta Robinson, and Baltimore took Haloti Ngata. Robinson's an above average corner. Ngata is a stud on the d-line, but I think everyone saw that was going to be the case. I want to be sure that we take the best player we can in the first round, and I'd like to know that we've got someone who can spot the little differences that separate good from great.
Baalke did a decent job on his first draft, but the Taylor Mays pick has me concerned a little in this department. Mays has all of the talent in the world, but we're still not sure if that talent will translate to the football field. With the exception of Willis, we've had some draft misses on the defensive side of the ball in the last few years. We can't miss with that first pick this year.