The San Francisco 49ers and New York Giants have met 42 times, including eight in the postseason. The two teams each have won 21. Thursday night's contest at Levi's Stadium in Santa Clara will break the deadlock. San Francisco comes in as 10.5 point favorites over a New York team which will be without four starters including star running back Saquon Barkley and the left side of its offensive line....
49ers look to avoid Giant upset: Five Burning Questions for Thursday Night Football
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