The 49ers (3-5) lost at home to the Arizona Cardinals (9-1) even though Kyler Murray and DeAndre Hopkins did not play.
Instant 49ers analysis: Defensive miscues let Colt McCoy dominate
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Recap: Short-handed Cardinals send 49ers to dismal 31-17 defeat
By Kirk Larrabee
Nov 7, 2021
It seemed like the San Francisco 49ers had a golden opportunity on their hands against the Arizona Cardinals on Sunday, with backup quarterback Colt McCoy under center for the Cardinals while starter Kyler Murray was sidelined with an ankle injury.
In addition, the Cardinals...
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