The Los Angeles Rams will host the San Francisco 49ers at SoFi Stadium in Inglewood, California, on Sunday, September 22, at 1:25 p.m. PT. Each week, the 49ers Webzone staff takes part in the annual NFL Pick 'Em contest, where writers and forum moderators predict the outcome of each game.
This week, all five participating staff members have picked the 49ers to defeat the Rams after Week 2's loss to the Minnesota Vikings. San Francisco is currently favored by 6.5 points.
Among fans in our NFL Pick 'Em contest, 94 percent are also predicting a 49ers victory, as of this post.
There are five Week 3 matchups with one-sided voting results. Fans overwhelmingly expect the Cleveland Browns to beat the New York Giants, the Tampa Bay Buccaneers to take down the Denver Broncos, the Las Vegas Raiders to top the Carolina Panthers, the Buffalo Bills to defeat the Jacksonville Jaguars, and the Cincinnati Bengals to overcome the Washington Commanders. Each predicted winner holds 96 percent of the fan votes.
The closest matchup in terms of fan predictions is Sunday's game between the Baltimore Ravens and the Dallas Cowboys, with 62 percent backing the Ravens to win.
Below is a breakdown of all 15 matchups for the upcoming slate of NFL games.
| Picks | Away | Home | Picks |
|---|---|---|---|
|
4%
|
Giants
|
Browns
|
96%
|
|
65%
|
Packers
|
Titans
|
35%
|
|
33%
|
Bears
|
Colts
|
67%
|
|
72%
|
Texans
|
Vikings
|
28%
|
|
32%
|
Eagles
|
Saints
|
68%
|
|
70%
|
Chargers
|
Steelers
|
30%
|
|
4%
|
Broncos
|
Buccaneers
|
96%
|
|
4%
|
Panthers
|
Raiders
|
96%
|
|
19%
|
Dolphins
|
Seahawks
|
81%
|
|
62%
|
Ravens
|
Cowboys
|
38%
|
|
94%
|
49ers
|
Rams
|
6%
|
|
77%
|
Lions
|
Cardinals
|
23%
|
|
89%
|
Chiefs
|
Falcons
|
11%
|
|
4%
|
Jaguars
|
Bills
|
96%
|
|
4%
|
Commanders
|
Bengals
|
96%
|