The San Francisco 49ers were decimated by injuries during a 33-10 loss to the Philadelphia Eagles on Sunday. The still-winless 49ers fall to 0-8, which is the worst start in franchise history, while the soaring Eagles improve to an NFL-best 7-1.

Below are some of the notable injuries that the 49ers suffered in Philadelphia.

Jimmie Ward

Safety Jimmie Ward suffered a forearm injury during the first quarter following a tackle on a 15-yard pass to Eagles tight end Trey Burton. After some time on the field, Ward was taken to the locker room for further observation and was ruled out. Rookie Adrian Colbert replaced him.

Garry Gilliam

Garry Gilliam, who started at right tackle in place of Trent Brown, suffered a knee injury in the second quarter and was ruled out. Zane Beadles replaced him but would switch to left tackle following another injury. Gilliam started because Brown suffered a concussion last week against the Dallas Cowboys and was not cleared in time to play against Philadelphia.

Joe Staley

Tackle Joe Staley exited the game after sustaining a gash beneath his right eye. The injury occurred following an interception by Eagles cornerback Jalen Mills when defensive lineman Fletcher Cox blocked Staley during the return. The veteran tackle was ruled out.

NBC Sports Bay Area reported that Staley was having trouble opening his right eye because of the cut.

Staley was replaced by Beadles, who had already replaced Gilliam on the right side. Rookie Erik Magnuson entered the game to take over at right tackle for Beadles.

Solomon Thomas

Defensive lineman Solomon Thomas, who was one of two first-round picks by the 49ers in April, suffered a knee injury during the second half.

The 49ers were already without their other first-round selection, linebacker Reuben Foster, who was inactive against Philadelphia. Foster, who has now missed six games this season, was limited during practices all week with a rib injury suffered last week against Dallas.

D.J. Jones

Rookie defensive tackle D.J. Jones also suffered a knee injury against Philadelphia. Jones has been a part of the 49ers defensive line rotation behind starter Earl Mitchell.

Pierre Garçon

During the game, the 49ers announced that wide receiver Pierre Garçon suffered a neck injury and was questionable to return.

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