Two San Francisco 49ers have been rules out for Sunday against the Cincinnati Bengals. Head coach Jim Tomsula stated on Friday that LB Michael Wilhoite and LG Alex Boone were definitely out. Wilhoite has a high ankle sprain while Boone has a sprained MCL.

LB Aaron Lynch and WR Torrey Smith are listed as questionable. Lynch remains in the concussion protocol this week. While he has practiced, he has done so in a blue no-contact jersey. Smith practiced for the first time on Friday after dealing with back issues.

A massive 18 players appeared as probable on the 49ers' injury report.

The 49ers and Bengals kick off at 1:25 PM on Sunday at Levi's Stadium.

San Francisco 49ers

Out: LG Alex Boone (knee), LB Michael Wilhoite (ankle)
Questionable: OLB Aaron Lynch (concussion), WR Torrey Smith (back, toe), CB Tramaine Brock (hamstring)
Probable: DT Arik Armstead (shoulder), WR Anquan Boldin (hamstring), LB Navorro Bowman (shoulder, finger), LB Ahmad Brooks (shoulder), CB Marcus Cromartie (hip), DT Quinton Dial (shoulder), RB Kendall Gaskins (concussion), LB Eli Harold (shoulder, hamstring), C Marcus Martin (ankle), TE Vance McDonald (concussion), T Erik Pears (knee), DT Mike Purcell (shoulder), S Eric Reid (shoulder), WR Jerome Simpson (finger), T Joe Staley (knee), S Jaquiski Tartt (ankle), G Andrew Tiller (knee), S Jimmie Ward (elbow)

Cincinnati Bengals

Out: QB Andy Dalton (thumb), TE Tyler Eifert (concussion), T Jake Fisher (concussion), S George Iloka (groin)
Probable: C Russell Bodine (finger), LB Vontaze Burfict (knee), CB Leon Hall (back), DE Michael Johnson (back), CB Adam Jones (foot), CB Dre Kirkpatrick (knee), T Andrew Whitworth (knee)