Losing Crabtree is definitely a blow to the offense, but there is potentially a positive. Both Crabtree and Boldin are slower possession receivers, and having them both on the field at the same time is kind of redundant. Opposing DB's wouldn't be scared of them taking the top off of the defense. Having another speedster on the opposite side of Boldin would open the field a bit for Kaep. I know VD's got some speed, but its not the same as a speedy WR on the outside. One thing our offense has sorely lacked is team speed, especially in the passing game.
Just one potential silver lining in a disappointing situation.
They need to take a tissue sample from Crabtree and search for crystalin structures, because this guys gotta be made out of glass.