San Francisco 49ers safety Adrian Colbert and linebacker Dekoda Watson have been ruled out for Sunday's game against the Indianapolis Colts. They join a list that includes linebacker Reuben Foster and safety Eric Reid, who have not been expected to play.

Foster is still recovering from a high-ankle sprain he suffered during Week 1 against the Carolina Panthers. Reid is recovering from a PCL injury he suffered during Week 2 against the Seattle Seahawks. Head coach Kyle Shanahan said on Friday that he is hopeful both players will be able to return to practice next week.

Wide receiver Marquise Goodwin, who suffered a concussion against the Arizona Cardinals on Sunday, is listed as questionable for Sunday. "I'd be surprised if he wasn't ready to go on Sunday," Shanahan told reporters on Friday.

Below are the official injury reports for the 49ers and the Colts. Also included are Friday's practice participation reports, which were provided by the 49ers Communications team.

San Francisco 49ers


Out
S Adrian Colbert (hamstring), LB Reuben Foster (ankle), S Eric Reid (knee), LB Dekoda Watson (groin)

Questionable
WR Marquise Goodwin (concussion)

Indianapolis Colts


Out
TE Jack Doyle (concussion, neck), CB Nate Hairston (quadricep), QB Andrew Luck (right shoulder)

Doubtful
RB Matt Jones (knee)

Questionable
CB Rashaan Melvin (hamstring, ankle), WR Chester Rogers (hamstring)

San Francisco 49ers Friday Practice


Did Not Participate In Practice
S Adrian Colbert (hamstring), LB Reuben Foster (ankle), S Eric Reid (knee), LB Dekoda Watson (groin)

Limited Participation in Practice
WR Marquise Goodwin (concussion)

Full Participation in Practice
LB Navorro Bowman (not injury related), RB Matt Breida (ankle), DE Elvis Dumervil (not injury related), RB Carlos Hyde (hip), T Joe Staley (not injury related), DE Pita Taumoepenu (ankle)

Indianapolis Colts Friday Practice


Did Not Participate In Practice
TE Jack Doyle (concussion, neck), RB Frank Gore (rest), RB Matt Jones (knee)

Limited Participation in Practice
QB Andrew Luck (right shoulder), CB Rashaan Melvin (hamstring, ankle), WR Chester Rogers (hamstring)

Full Participation in Practice
S Matthias Farley (quadricep), CB Nate Hairston (quadricep), C Ryan Kelly (foot), RB Marlon Mack (shoulder), G Jack Mewhort (rest), CB Chris Milton (hamstring), LB Anthony Walker (hamstring), CB Quincy Wilson (knee)