The San Francisco 49ers are facing the Arizona Cardinals in a Week 3 matchup at Levi's Stadium in Santa Clara, California.
Below are the latest in-game injury updates for the 49ers. This article will be updated in real time as new information becomes available.
Players are listed in order of most recent report.
LB Dre Greenlaw (quad, questionable)
Dre Greenlaw was slow to get up in the fourth quarter and was declared questionable to return due to a quad injury.
CB Renardo Green (concussion, cleared to return)
Renardo Green was seen entering the medical tent during the third quarter. The 49ers announced that he is being evaluated for a concussion.
Update: Green returned to the game.
DT Gracen Halton (cramping, cleared to return)
Gracen Halton was slow to get up after an extra-point attempt during the third quarter. After some time on the sideline, he walked to the locker room with members of the training staff.
The 49ers announced that Halton is dealing with cramping.
Update: Halton returned to the game.
LT Trent Williams (stinger, questionable)
Trent Williams was carted to the locker room in the third quarter. The 49ers announced that he has a stinger and is questionable to return.
Vederian Lowe replaced him at left tackle.
Now Trent Williams is heading to the locker room on a cart 😔 pic.twitter.com/RO4FQSKs4Q
— 49ers on NBCS (@NBCS49ers) September 27, 2026
WR Mike Evans (rib, out)
Mike Evans was in pain after a play late in the second quarter. It took him some time to make his way to the bench, where he was evaluated.
They eventually carted Evans to the locker room.
Mike Evans was carted off just before halftime pic.twitter.com/vE6AIpclkD
— 49ers on NBCS (@NBCS49ers) September 27, 2026
CB Deommodore Lenoir (concussion, cleared to return)
Deommodore Lenoir was shaken up while making a tackle in the second quarter. He collided helmet-to-helmet with teammate linebacker Fred Warner.
Jack Jones replaced Lenoir, who entered the medical tent for evaluation before eventually heading to the locker room.
The 49ers announced that Lenoir is being evaluated for a concussion.
Update: Lenoir returned to the game in the second half.
Deommodore Lenoir had to head to the locker room after exiting today's game pic.twitter.com/eELxrTFANW
— 49ers on NBCS (@NBCS49ers) September 27, 2026
More info on: Mike Evans, Renardo Green, Dre Greenlaw, Gracen Halton, Jack Jones, Deommodore Lenoir, Vederian Lowe, Fred Warner, Trent Williams
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