The 49ers changed Brandon Aiyuk's status to "reserve/left squad" on Saturday after a season-long mystery of when he might return from last year's knee injury.
49ers change classification of Brandon Aiyuk’s delayed comeback
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49ers add WR Brandon Aiyuk to reserve/left squad list, likely assuring offseason split
49ers add WR Brandon Aiyuk to reserve/left squad list, likely assuring offseason split
By Marc Adams
Dec 13, 2025
According to Matt Maiocco of NBC Sports Bay Area, the San Francisco 49ers have placed WR Brandon Aiyuk on the reserve/left squad list. This move makes Aiyuk ineligible to return to action for the remainder of the 2025 season, and per Maiocco, all but assures an offseason split....
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