Five weeks into the 2025 NFL season, nobody's perfect -- and a new team sits atop Eric Edholm's Power Rankings. Who's up? Who's down? Check out the updated league hierarchy, 1-32.
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NFL Power Rankings, Week 6: Lions leapfrog Bills and Eagles to claim No. 1 spot; Chargers keep falling
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49ers in Week 6 power rankings: Experts react to injury-defying run
By David Bonilla
Oct 7, 2025
The San Francisco 49ers are riding the momentum of their thrilling overtime victory against the Los Angeles Rams as they prepare for a Week 6 matchup with the Tampa Bay Buccaneers at Raymond James Stadium.
Despite dealing with multiple injuries, the 49ers battled through...
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