Frustrating mistakes blow an great opportunity to notch their first win of the season.
New 49ers regime begins 0-5
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Recap: 49ers Drop to 0-5 After 26-23 Overtime Loss to Colts
By Bret Rumbeck
Oct 8, 2017
The Indianapolis Colts set up a day to retire former quarterback Peyton Manning's jersey. Lucas Oil Stadium was covered in blue towels and No. 18 jerseys.
Coming off an overtime loss to Arizona, the San Francisco 49ers showed up to try and spoil the celebration.
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