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- January 2, 2022; 1:05 pm (PT)
- 49ers -12.5; O/U 43.5
- Venue: Levi's Stadium
Injury Report
49ers:
Out: LB Azeez Al-Shaair (knee), LB Dre Greenlaw (groin), DL Maurice Hurst (calf)
Doubtful: QB Jimmy Garoppolo (right thumb), S Talanoa Hufanga (knee)
Questionable: RB Elijah Mitchell (knee)
Texans:
Questionable: WR Chris Conley (knee), S A.J. Moore (illness), CB Jimmy Moreland (illness)
