San Francisco 49ers vs Buffalo Bills odds and pick - Week 13, 2020

Dec 3, 2020 at 10:35 AM

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Robert Hanashiro-USA TODAY Sports

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Poll

  • What is your best bet for 49ers vs Bills on 12/7/20?
  • 49ers +1
    65%
  • Bills -1
    17%
  • Under 48
    12%
  • Over 48
    7%
  • 481 votes
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