These 6 49ers players are inactive vs. Buccaneers
Published Oct 12, 2025 at 11:57 AM
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The San Francisco 49ers have released the list of inactive players for their Week 6 matchup against the Tampa Bay Buccaneers. These six players will not suit up for the game.
Inactives:
On Friday, the San Francisco 49ers officially ruled out five players, filling most of their inactive list for Sunday's matchup. Those already known to be sidelined are defensive linemen Kevin Givens and Yetur Gross-Matos, wide receivers Ricky Pearsall and Jordan Watkins, and quarterback Brock Purdy.
Defensive lineman Kevin Givens (pectoral) had his practice window opened last week, but he has yet to be activated from injured reserve.
Defensive tackles Alfred Collins (knee) and Kalia Davis (hand), wide receiver Jauan Jennings (ankle, rib), quarterback Mac Jones (knee, oblique), and cornerback Upton Stout (ankle) were listed as questionable. All are active.
Jones is making his fourth start of the season in place of Purdy.
On Saturday, the 49ers activated safety Malik Mustapha from the physically unable to perform (PUP) list, marking his return from an ACL injury. He is active against the Buccaneers. To make room on the roster, the team waived defensive end Robert Beal Jr. Additionally, defensive lineman Trevis Gipson was elevated from the practice squad for the second straight game.
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