49ers at Cardinals, Week 16 predictions: Arizona the overwhelming pick to win

Dec 26, 2020 at 11:44 AM


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Matt Kartozian-USA TODAY Sports

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The Arizona Cardinals are set to host the San Francisco 49ers at State Farm Stadium in Glendale, Arizona on Saturday, December 26 at 1:30 p.m. PT. Each week, the 49ers Webzone staff predicts the winner within its annual NFL Pick 'em contest. That includes writers and forum moderators.

None of the seven participating staff members this week selected the 49ers to beat the Cardinals. San Francisco is currently a six-point underdog.

As for all the fans who are taking part in our NFL Pick 'em contest, 90 percent have the Cardinals winning the game, as of this post.

Of all the Week 16 game predictions, the two most lopsided results come from Sunday's matchups between the New York Giants and the Baltimore Ravens and between the Cleveland Browns and the New York Jets. Voting has 100 percent of fans selecting the Ravens and Browns to win their respective games.

The closest matchup, when it comes to the predictions, is between the Indianapolis Colts and the Pittsburgh Steelers on Sunday, with 54 percent selecting the Colts to win the game.

Picks Away Home Picks
97%
Buccaneers
Lions
3%
10%
49ers
Cardinals
90%
81%
Dolphins
Raiders
19%
0%
Giants
Ravens
100%
54%
Colts
Steelers
46%
2%
Falcons
Chiefs
98%
13%
Bengals
Texans
87%
100%
Browns
Jets
0%
94%
Bears
Jaguars
6%
22%
Panthers
Washington
78%
10%
Broncos
Chargers
90%
43%
Rams
Seahawks
57%
70%
Eagles
Cowboys
30%
22%
Titans
Packers
78%
97%
Bills
Patriots
3%

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