The San Francisco 49ers are preparing for their Week 5 contest against the Arizona Cardinals on Sunday at Levi's Stadium in Santa Clara, California.

When the 49ers took the field for Wednesday's practice, guards Mike Person and Laken Tomlinson were the only starting offensive linemen taking part. Center Weston Richburg and tackles Joe Staley and Mike McGlinchey are each dealing with a knee injury. Head coach Kyle Shanahan said on Monday that each would likely be questionable this week, but the team's official game status and injury report won't be released until Friday.

Other injury notes from Wednesday:

  • RB Matt Breida was in a blue no-contact jersey, per Bay Area News Group.
  • WR Marquise Goodwin was paired with CB Richard Sherman in rehab drills.
  • S Jaquiski Tartt returned to practice.
  • S Adrian Colbert was a full participant in practice. He was active against the Los Angeles Chargers but was limited to playing on special teams.

Below are Wednesday's practice participation reports for both the 49ers and Cardinals, which were provided by the 49ers Communications staff.

San Francisco 49ers Wednesday Practice

Did Not Participate In Practice
WR Marquise Goodwin (hamstring, quadricep), T Mike McGlinchey (knee), WR Dante Pettis (knee), C Weston Richburg (knee), CB Richard Sherman (calf), T Joe Staley (knee)

Limited Participation in Practice
RB Matt Breida (shoulder), G Mike Person (knee)

Full Participation in Practice
S Adrian Colbert (hip), G Joshua Garnett (toe), RB Alfred Morris (knee), S Jaquiski Tartt (shoulder), CB Ahkello Witherspoon (ankle, hip)

Arizona Cardinals Wednesday Practice

Did Not Participate In Practice
CB Bene' Benwikere (neck), WR Larry Fitzgerald (hamstring, back), DE Markus Golden (knee), DT Corey Peters (elbow)

Limited Participation in Practice
LB Josh Bynes (wrist), TE Jermaine Gresham (achilles), T Andre Smith (elbow), CB Jamar Taylor (back), T John Wetzel (shoulder)

Full Participation in Practice
T Korey Cunningham (thumb)