| 49ers Schedule |
| Day |
Date |
Opponent |
Time |
Result |
Score |
| Preseason |
| Fri | 8/8 | at Raiders | 7:00p | - | |
| Sat | 8/16 | Packers | 6:00p | - | |
| Thur | 8/21 | at Bears | 6:00p | - | |
| Fri | 8/29 | Chargers | 7:00p | - | |
| Regular Season |
| Sun | 9/7 | Cardinals | 1:15p | - | |
| Sun | 9/14 | at Seahawks | 1:05p | - | |
| Sun | 9/21 | Lions | 1:05p | - | |
| Sun | 9/28 | at Saints | 10:00a | - | |
| Sun | 10/5 | Patriots | 1:15p | - | |
| Sun | 10/12 | Eagles | 1:15p | - | |
| Sun | 10/19 | at Giants | 10:00a | - | |
| Sun | 10/26 | Seahawks | 1:15p | - | |
| BYE |
| Mon | 11/10 | at Cardinals | 5:30p | - | |
| Sun | 11/16 | Rams | 1:05p | - | |
| Sun | 11/23 | at Cowboys | 10:00a | - | |
| Sun | 11/30 | at Bills | 10:00a | - | |
| Sun | 12/7 | Jets | 1:05p | - | |
| Sun | 12/14 | at Dolphins | 10:00a | - | |
| Sun | 12/21 | at Rams | 10:00a | - | |
| Sun | 12/28 | Redskins | 1:15p | - | |
| All Times Pacific |