As the 49ers make preparations for another prime-time matchup, they may be doing so with a diminished roster. The 49ers lost their best defender in their win over St. Louis on Dec. 4, when linebacker Patrick Willis pulled his hamstring. Then in their 21-19 loss in Arizona, their best offensive linemen, Joe Staley, left with what was termed a "head injury."
49ers rewind: Staley’s status will be watched
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