Inactives:
- OL Daniel Brunskill (hamstring)
- TE George Kittle (groin)
- QB Brock Purdy
- DL Kemoko Turay
- OL Nick Zakelj
Tight end George Kittle was not expected to play in this Week 2 matchup. He continues to deal with the groin strain suffered on September 5. There was some hope that the All-Pro player would find his way onto the field against the division-rival Seahawks, but a return in Week 3 against the Denver Broncos is likely.
The 49ers didn't make any roster moves on Saturday, when they typically shuffle players into the lineup from the practice squad.
Offensive lineman Daniel Brunskill was the only 49ers player ruled out in Friday's game status report. He is attempting to return from a hamstring injury suffered during the preseason and, like Kittle, has yet to make his 2022 season debut.
Wide receiver Danny Gray and running back Tyrion Davis-Price were both inactive for Week 1. They will be suited up against the Seahawks.
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