San Francisco 49ers defensive end Nick Bosa is set to return to practice Wednesday after missing the team's last five games with a calf injury. Head coach Kyle Shanahan confirmed that Bosa will be a limited participant as the 49ers prepare for Sunday's matchup against the Las Vegas Raiders at Levi's Stadium.
The 49ers are coming off their bye week, allowing several injured players to make progress toward returning to the lineup.
Bosa has been sidelined since suffering the calf injury and has not practiced during his absence.
"He has made progress," Shanahan said. "That's why he's going to be limited today."
Mike Evans injury update
Wide receiver Mike Evans continues to work his way back from Achilles tendinitis, which forced him to miss the 49ers' Week 7 game against the Atlanta Falcons. He will not return to practice Wednesday.
Shanahan provided an update on Evans' recovery.
"I think we've made a lot of progress," he said. "I think he's going in the right direction, and it's something we've definitely got to be smart with. We're not going to overly do it. We just want to wait until he's healthy and he's still working his way to get there."
Other 49ers injury updates
A couple of other 49ers players are expected to miss Wednesday's practice: Wide receiver Deebo Samuel (hamstring) and defensive back Siran Neal (knee, foot).
Regarding Samuel, Shanahan said, "He's making progress. He can't go today. I'd be surprised if he can go this week, but he's making good progress."
Running back Christian McCaffrey (hamstring) also will not practice Wednesday, but Shanahan left open the possibility of a return Thursday.
"I think he had a good week," Shanahan said of McCaffrey. "His wasn't as bad as Deebo's and stuff. I mean, he's not going today, but hopefully he can have a chance to be limited tomorrow."
Linebacker Garret Wallow (hamstring), safety Marques Sigle (ankle), linebacker Luke Gifford (groin), and cornerback Upton Stout (shoulder) are expected to be limited participants.
Shanahan also noted that the 49ers will likely hold defensive tackle C.J. West out of practice this week and reassess his status next week.
49ers open practice windows for two injured players
The 49ers are opening practice windows for two players on injured reserve: wide receiver Demarcus Robinson (ankle) and cornerback Nate Hobbs (adductor). Both are expected to participate in a limited capacity during Wednesday's practice.
"He was out there in walk-through, and we'll see him in full action, just like Nick, just like Hobbs, just like Sigle," Shanahan said of Robinson. "But all those guys will be out there for the first time today."
The 49ers today announced they have opened the practice window for CB Nate Hobbs (Injured Reserve List) and WR Demarcus Robinson (Injured Reserve List).
— San Francisco 49ers (@49ers) November 4, 2026
De'Zhaun Stribling injury update
Shanahan was also asked about rookie wide receiver De'Zhaun Stribling, who has been on injured reserve since suffering an ankle injury in Week 1. The coach previously expressed hope that Stribling could return sometime in December.
"It's a long ways away," Shanahan said. "I'm hoping he can return, first of all, which is the expectation. I mean, I'd be surprised if he didn't. And as he gets closer to running and stuff, and kind of having an idea how—usually, once he's a week away, I start asking how he's going to be in practice next week. So if it's kind of a build-up week, or if he's in a spot where he's ready to go, and we've got to get him a couple days to get ready to play. So, I'm still probably over a month away from that."
More info on: Nick Bosa, Mike Evans, Luke Gifford, Nate Hobbs, Christian McCaffrey, Siran Neal, Demarcus Robinson, Deebo Samuel, Marques Sigle, Upton Stout, De'Zhaun Stribling, Garret Wallow, C.J. West
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