The San Francisco 49ers placed Brandon Aiyuk on the reserve/left squad list on Saturday, which officially ends his season, NFL Network Insider Ian Rapoport reported.
Niners place Brandon Aiyuk on reserve/left squad list, ending WR’s season
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49ers add WR Brandon Aiyuk to reserve/left squad list, likely assuring offseason split
By Marc Adams
Dec 13, 2025
According to Matt Maiocco of NBC Sports Bay Area, the San Francisco 49ers have placed WR Brandon Aiyuk on the reserve/left squad list. This move makes Aiyuk ineligible to return to action for the remainder of the 2025 season, and per Maiocco, all but assures an offseason split....
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