BOX SCOREQuarterback Brock Purdy’s return to the 49ers’ starting lineup on Sunday went as well as San Francisco could have hoped.Purdy and the 49ers romped over the Arizona Cardinals, 41-22, at State Farm Stadium to improve to 7-4 this season.Playing in his first game since Week 4, and his third contest overall this season, Purdy completed 19 of 26 passes for 200 yards and three touchdowns. He didn’t throw any interceptions, though he came close on a few instances when he dangerously threw into traffic.Christian McCaffrey had a productive day, gaining 81 yards on 13 carries and scoring two rushing touchdowns. He also caught five passes for 40 yards and one touchdown.Purdy’s favorite target, tight end George Kittle, caught six passes for 67 yards and two touchdowns. Career touchdown No. 50 for Kittle pic.twitter.com/Pr0iG5TYrL — 49ers on NBCS (@NBCS49ers) November 16, 2025 Wide receiver/kick returner Skyy Moore got the 49ers off to a great start, taking the opening kickoff 98 yards to the Cardinals’ 1-yard line, setting up McCaffrey’s first touchdown of the day.A few minutes later, Purdy hit Kittle for a pretty 30-yard...
What we learned as Brock Purdy, CMC, Kittle fuel 49ers’ big win vs. Cardinals
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Recap: 49ers romp over error-prone Cardinals in 41-22 victory
Recap: 49ers romp over error-prone Cardinals in 41-22 victory
By Kirk Larrabee
Nov 16, 2025
Chances are the San Francisco 49ers would have been able to come out of Arizona on Sunday with their seventh win of the season without any extra help from the Cardinals, but they got a bunch of it anyway, and it certainly made their latest victory quite a bit easier.
The...
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