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49ers vs. Rams recap: Short-handed SF beat up by rivals in 42-26 loss

Published Nov 9, 2025 at 12:00 PM
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What to Know The San Francisco 49ers (6-4) were unable to secure a season sweep of their NFC West division rival after a 42-26 loss to the Los Angeles Rams (7-2) on Sunday at Levi’s Stadium. Despite the final score, backup QB Mac Jones had a nice game, completing 33 of 39 passes for 319 yards with three touchdowns , one interception and a 115.7 passer rating. Running back Christian McCaffrey was fairly limited on the ground, picking up 30 rushing yards on 12 carries to go with 66 receiving yards on eight catches. Brian Robinson Jr., Luke Farrell, Jauan Jennings and George Kittle scored San Francisco’s four touchdowns in the loss. Read below for all the game highlights, news, analysis and postgame press conferences from Levi’s Stadium in Santa Clara:

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