Purdy's toe injury flared up after Sunday's loss to Jaguars, while Pearsall suffered a knee injury in the loss.
Brock Purdy, 49ers’ top receivers ruled out for Thursday night at Rams
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49ers vs. Rams final injury report: Purdy, Pearsall, Jennings ruled out for TNF
By David Bonilla
Oct 1, 2025
The San Francisco 49ers are preparing for their Week 5 contest against the Los Angeles Rams on Thursday at SoFi Stadium in Inglewood, California. Both teams have released their official injury reports, which are provided below.
The 49ers will turn to Mac Jones under center, as...
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