Mac Jones is officially getting his second start for the 49ers. San Francisco and Arizona each have key starters inactive for Sunday's NFC West matchup, as Brock Purdy, Jauan Jennings, and Cardinals left tackle Paris Johnson are all inactive for the contest. Purdy and Jennings were officially downgraded to out earlier on Sunday. Johnson was listed as questionable after he was limited with a knee injury in all three days of practice this week. Arizona's other inactives are cornerback Will Johnson, running back Bam Knight, linebacker Xavier Thomas offensive lineman Will Hernandez, and receiver Xavier Weaver.The 49ers' inactives are Purdy, Jennings, running back Jordan James, defensive lineman Jordan Jefferson, linebacker Nick Martin, and receiver Jordan Watkins.
Brock Purdy, Jauan Jennings, Paris Johnson all inactive for 49ers-Cardinals
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Purdy, Jennings among 6 49ers players inactive vs. Cardinals; Colby active
Purdy, Jennings among 6 49ers players inactive vs. Cardinals; Colby active
By David Bonilla
Sep 21, 2025
The San Francisco 49ers have released the list of inactive players for their Week 3 matchup against the Arizona Cardinals. These six players will not suit up for the game.
Inactives:
RB Jordan James
DL Jordan Jefferson
WR Jauan Jennings (ankle, shoulder)
LB Nick Martin
QB...
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