SANTA CLARA — The 49ers enter the weekend with a lot more questions than answers at wide receiver.Jauan Jennings is listed as questionable for the 49ers’ Week 2 game against the New Orleans Saints with a shoulder injury.He returned to practice on Friday, which suggests a likelihood that he will be available to play. Jennings even caught a pass in the end zone during warmups and performed a dunk over the crossbar. Air Jauan pic.twitter.com/cQcsPMmx0R — 49ers on NBCS (@NBCS49ers) September 12, 2025 Left tackle Trent Williams is also listed as questionable. He was listed as limited at practice due to a knee injury. He was seen with a member of the 49ers’ strength and conditioning staff Friday as the team began its final practice before leaving for New Orleans.The 49ers would likely turn to Spencer Burford to start at left tackle if Williams, an 11-time Pro Bowl player, is unavailable. Burford, a four-year veteran, has 29 career starts but none at tackle. He played right guard for the 49ers in 2022 and ’23.The 49ers officially ruled out quarterback Brock Purdy with a toe injury. He also came out of the first game of the season with a...
Brock Purdy out for 49ers-Saints; Jauan Jennings, Trent Williams questionable
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