Where 49ers can turn with top two running backs headed to IR

The 49ers will to need to add to their running backs room after losing both Christian McCaffrey and Jordan Mason to injuries in their 35-10 loss to the Buffalo Bills. Both running back will be placed on injured reserve, which means they will miss a minimum of four games starting in Week 14. McCaffrey suffered a PCL injury that coach Kyle Shanahan estimates will require at least six weeks of recovery, while Mason suffered a high ankle sprain. Speaking to Mason after the game, the third-year back did not seem to be dealing with an ankle injury, but was seen with a wrap on his right arm in the locker room before the team flew back to the Bay Area. The 49ers now will lean on rookie Isaac Guerendo, who has appeared in 12 games this season, registering 42 carries for 236 yards and two touchdowns. Fourth-year running back Patrick Taylor also will be in the mix. "We have Guerendo, obviously, who will be up," Shanahan said on Monday via conference call. "We have Patrick here, who is on our practice squad, who will definitely be bumped up now. "[Taylor] was on our roster earlier this year before Christian came back. We will most likely have to look for another." Guerendo was the 49ers'...