The 49ers' 2022 season opens at Chicago, followed by a home opener against Seattle and two games against the Rams before a Week 9 bye.
49ers’ schedule: Open in Chicago, Rams twice before bye, New Year’s in Vegas
Published May 12, 2022 at 6:00 PM
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Complete 2022 San Francisco 49ers Schedule Revealed
By David Bonilla
May 12, 2022
The NFL revealed its complete 272-game 2022 regular-season schedule on Thursday at 5:00 p.m. PT. NFL Kickoff Weekend will begin on Thursday, September 8, culminating with Super Bowl LVII on February 12, 2023, at State Farm Stadium in Glendale, Arizona.
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