San Francisco 49ers TE Vance McDonald was injured during a punt return in the second quarter of the team's matchup with the Steelers in Pittsburgh.

Following the play, the medical staff was looking at his right knee after he walked off the field on his own.

The Steelers, who are passing with ease against the 49ers defense, scored on the next play to take a 22-3 lead.

McDonald is questionable to return to the game.