Videos are auto-populated by an affiliate. This site has no control over the videos that appear above.
Interim head coach Jim Tomsula led the San Francisco 49ers to a 38-7 rout over the visiting Arizona Cardinals in their final game of the 2010 season.
In what could be his last game in San Francisco, Alex Smith was 15 of 29 for 276 yards and two touchdowns.
Brian Westbrook carried the ball for 79 yards and two more touchdowns.
Next, the 49ers look to the offseason to hire a new G.M. and head coach. Stay here during the entire offseason as 49erswebzone.com covers the G.M. hiring, head coach search, free agency, the NFL Draft, and much more.
Brock Purdy reflects on lessons learned during challenging 49ers season
By David Bonilla
Dec 6
San Francisco 49ers quarterback Brock Purdy acknowledges that this season has been anything but easy. The team's 5-7 record and three-game losing streak reflect the struggles. Purdy has faced his own challenges, including a shoulder injury that sidelined him during the loss to...
(Episode 395) — Al Sacco and Brian Renick react to the 49ers' season effectively being over, Deebo's performance confirming that he does not deserve to be on the 49ers anymore, the lack of flow on offense, the defense doing their part against the Rams, which defensive...
Deebo Samuel, De'Vondre Campbell succumb to frustration as 49ers season washes away
By JD Salazar
Dec 12
In a rain-soaked stadium, facing their mirror image once again, the San Francisco 49ers stood by and let their season slip away.
If not officially, the 12-6 loss to the Los Angeles Rams marks the end of San Francisco's faint playoff hopes. The 49ers, who now fall to 6-8, have...
49ers mailbag: What do the 49ers have left in the tank for the last four games? Will SF bring back Robert Saleh? Can Brock Purdy beat good teams?
By Marc Adams
Dec 11
It's always a big week when the San Francisco 49ers play the Los Angeles Rams. In 2021, the rivalry became even bigger when the 49ers had to win in the season's final week, in Los Angeles, to make it into the playoffs. On Thursday night, the 49ers must win again to keep their...