The San Francisco 49ers are preparing for their Week 15 contest against the Tennessee Titans on Sunday at Levi's Stadium in Santa Clara, California.
Defensive end Sam Okuayinonu and linebackers Tatum Bethune and Nick Martin remain sidelined.
The two players who received veteran rest days on Wednesday—running back Christian McCaffrey and tackle Trent Williams—returned to the field. However, McCaffrey was limited due to an illness.
During a radio interview, when asked whether McCaffrey's illness is something to worry about, an unconcerned Kyle Shanahan responded, "No, he'll be alright."
Reporters saw McCaffrey at the very start of practice, but after about 10 minutes he was no longer participating. (He didn't look terrific in the locker room after practice either). https://t.co/mKtotPT5rs
— Matt Barrows (@mattbarrows) December 11, 2025
Defensive tackle Kevin Givens also returned after missing Wednesday's session due to a personal matter.
Fullback Kyle Juszczyk remains a limited practice participant after suffering a rib fracture against the Cleveland Browns.
Additionally, San Francisco opened the practice window for defensive end Yetur Gross-Matos.
When asked why the 49ers waited until Thursday to open Gross-Matos' practice window, Shanahan said, "Just because of how the whole offseason went with him, and our plan this year. We don't ever practice him two days in a row, Wednesday and Thursday, so he only practices on Thursdays, regardless, even before he got hurt."
General manager John Lynch discussed Gross-Matos on Thursday: "He's an excellent football player. He's a guy who can play outside, but then, is probably at his best when he moves inside on nickel or pass situations. He's a really effective football player."
Yetur Gross-Matos is back at practice today! pic.twitter.com/dYbSmb6cUS
— 95.7 The Game (@957thegame) December 11, 2025
Below are Thursday's practice participation reports for both the 49ers and Titans, which were provided by the 49ers Communications staff.
San Francisco 49ers Thursday Practice
Did Not Participate In Practice- LB Tatum Bethune (ankle)
- LB Nick Martin (concussion)
- DE Sam Okuayinonu (ankle)
Limited Participation in Practice
- FB Kyle Juszczyk (ribs)
- RB Christian McCaffrey (illness)
- DT Kevin Givens (not injury related - personal matter)
- K Eddy Piñeiro (right hamstring)
- QB Kurtis Rourke (knee)
- T Trent Williams (not injury related - resting player)
Tennessee Titans Thursday Practice
Did Not Participate In Practice- LB James Williams (illness)
Limited Participation in Practice
- CB Jalyn Armour-Davis (Achilles)
- C Lloyd Cushenberry (foot)
- T Dan Moore (neck)
- DT C.J. Ravenell (toe)
- G Kevin Zeitler (not injury related - resting player, groin)
Full Participation in Practice
- TE Chigoziem Okonkwo (not injury related - resting player)
- RB Tony Pollard (not injury related - resting player)
- DT Jeffery Simmons (not injury related - resting player)
- DT Shy Tuttle (concussion)