The San Francisco 49ers return to Levi's Stadium for the 2022 home opener as they take on the NFC rival Seattle Seahawks. The Niners will be looking to earn their first division win of 2022 and their 10th home win all-time against the Seahawks.
The 49ers aim to bounce back after a 19-10 loss to the Chicago Bears. On offense, WR Deebo Samuel carried the ball eight times for 52 yards, including a six-yard touchdown run. RB Elijah Mitchell eclipsed 1,000 career rushing yards after registering 41 yards on six carries. QB Trey Lance completed 13 of his 28 pass attempts for 164 yards while also registering a team-high 54 rushing yards on 13 attempts.
Defensively, the Niners held the Bears to just 204.0 total yards and only 99 rushing yards. S Talanoa Hufanga led the team with a career-high 11 tackles and snagged his first career interception. DE Nick Bosa and DE Samson Ebukam both got to Bears QB Justin Fields in the backfield, registering their first sacks of the season.
The 49ers Communications staff provided the above breakdown.
Below is everything you need to know to follow the upcoming game.
When does the game start?
Sunday, September 18 at 1:05 p.m. PT
Where is the game being played?
Levi's Stadium in Santa Clara, California
Who are the head coaches?
Seahawks: Pete Carroll
What channel is the game on?
Network: FOX
Play-By-Play: Adam Amin
Color Analyst: Mark Schlereth
Sideline Reporter: Kristina Pink
NFL Sunday Ticket subscribers can find the game on channel 713 on DirecTV.
What areas will receive the broadcast?
For those without NFL Sunday Ticket, the broadcast will be viewable within the markets designated below.
Where can I stream the game?
NFL Sunday Ticket subscribers can stream the game using the service's official mobile app. NFL+ subscribers can stream the game in its entirety once the matchup has been completed.
Bay Area fans can stream the game through the official 49ers app or at 49ers.com.
Where can I listen to the radio broadcast?
Bay Area fans can listen on KNBR 680 AM/104.5 FM and The Bone 107.7 FM, where Greg Papa and Tim Ryan will call the game.
Jesús Zárate will call the game in Spanish. That broadcast can be listened to at 49ers.com/news/Espanol.
Seattle area fans can listen on Seattle Sports 710 AM and KIRO Newsradio 97.3 FM, where Steve Raible and Dave Wyman will call the game.
NFL+ subscribers can listen to the game through that service.
San Francisco: SiriusXM 135 or 232 and the SXM App
Seattle: SiriusXM 108 or 387 and the SXM App
Game discussion
Fans can discuss the game within our Niner Talk forum.
How has this series played out historically?
Matchups: 47
Series Record: Seahawks lead series 30-17
49ers Home Record vs. Seahawks: Seahawks lead series 13-9
49ers Away Record vs. Seahawks: Seahawks lead series 17-8
First Meeting: 9/26/76, 49ers win 37-21, at Sea.
Last Meeting: 12/5/21, Seahawks win 30-23, at Sea.
Current Streak: Lost 4
Longest 49ers Win Streak: 4 (12/12/10 – 10/18/12)
Longest Seahawks Win Streak: 10 (1/19/14 – 12/2/18)
Most 49ers Points: 40 (12/12/10): 49ers win 40-21, at SF
Most Seahawks Points: 43 (12/2/18): Seahawks win 43-16, at Sea.
49ers Shutouts: None
Seahawks Shutouts: 2 (Last 11/12/07), Seahawks win 24-0, at Sea.
49ers Notes
- QB TREY LANCE totaled 218 yards (164 pass, 54 rush) in Week 1. He passed for 249 yards & 2 TDs vs. 1 INT for a 116 passer rating in his only career home start (10/3/21 vs. Hou.). He had 198 yards (157 pass, 41 rush) & 2 TDs vs. 0 INTs for a 117.1 rating in the last home meeting.
- RB JEFF WILSON had 88 scrimmage yards (76 rush, 12 rec.) & 2 TDs (1 rush, 1 rec.) in his last home game vs. Sea. (1/3/21).
- WR DEEBO SAMUEL had 66 scrimmage yards (52 rush, 14 rec.) & 12th-career rushing TD in Week 1. He had 754 scrimmage yards (94.3 per game) & 9 TDs (5 rec., 4 rush) in 8 home games last season. Samuel has 247 scrimmage yards (134.7 per game) & 3 TDs (2 rec., 1 rush) in 3 career games vs. Sea. He aims for his 4th in a row vs. Sea. with 5+ catches & 100+ rec. yards. He had 2 rec. TDs in the last home meeting.
- TE GEORGE KITTLE had 9 catches for 181 yards & 2 rec. TDs in the last meeting. Since 2017, ranks 2nd in rec. yards (4,489) & 3rd in receptions (335) among TEs.
- DL NICK BOSA had his 1st sack of the season last week & has 25.5 sacks in 36 career games. He had a sack in 3 of his final 4 home games in 2021. He had a sack & FF in the last meeting & aims for his 3rd in a row vs. Sea. with a sack.
- DL SAMSON EBUKAM had a sack last week. He had a TFL in 4 of his past 5.
- LB FRED WARNER had 74 tackles (9.3 per game) in 8 home games in 2021. He has 5 TFLs in his past 5 games vs. Sea. & aims for his 3rd in a row vs. Sea. with 9+ tackles.
- S TALANOA HUFANGA led the team with a career-high 11 tackles & had his 1st-career INT in Week 1. He was 1 of 3 players (Minkah Fitzpatrick & Marcus Williams) with 10+ tackles & an INT last week.
- CB CHARVARIUS WARD had a PD last week. He had a PD in his only career game vs. Sea. (12/23/18 w/ KC).