On Wednesday, the San Francisco 49ers signed safety Doug Middleton to the practice squad. One day later, the team placed him on the injured reserve list.
The situation has prompted the 49ers to re-sign safety Kai Nacua to the practice squad. San Francisco released Nacua on Wednesday as part of a move to make room on the practice squad for Middleton and linebacker Justin March.
The 49ers initially signed Nacua to the practice squad on November 24, 2020. He spent part of last season on the active roster and signed a one-year extension to remain with the team on February 11.
Nacua entered the NFL with the Cleveland Browns in 2017 as an undrafted free agent out of BYU. He has appeared in 22 games with three starts while recording 15 tackles, a tackle for a loss, and a quarterback hit in his career.
Rams WR Puka Nacua expected to play vs. 49ers in NFC West clash
By David Bonilla
Nov 5
Los Angeles Rams head coach Sean McVay expects wide receiver Puka Nacua to suit up against the San Francisco 49ers this Sunday at Levi's Stadium, according to ESPN's Adam Schefter. The NFC West showdown carries major playoff implications, with both teams sitting at six...
49ers injury news: Pearsall expected to practice, no Aiyuk yet, Purdy update
By David Bonilla
Nov 10
Following Sunday's loss to the Los Angeles Rams, San Francisco 49ers head coach Kyle Shanahan told reporters there were no new injuries to report—a rare bit of good news for a team that's battled through a string of setbacks during an injury-plagued 2025 season.
However,...
49ers practice and media schedule ahead of Week 11 matchup vs. Cardinals
By Site Staff
Nov 11
The San Francisco 49ers will hold three full practices this week as they prepare for their Week 11 matchup against the Arizona Cardinals.
Head coach Kyle Shanahan, defensive coordinator Robert Saleh, and offensive coordinator Klay Kubiak are scheduled to speak with the media....
San Francisco 49ers head coach Kyle Shanahan spoke to reporters ahead of Wednesday's practice—the first of the week—as the team prepares for its Week 11 matchup against the Arizona Cardinals. He shared encouraging updates on the team's injury situation.
Quarterback Brock...
