San Francisco 49ers wide receiver Pierre Garçon (shoulder, knee) and cornerbacks K'Waun Williams (shoulder) and Ahkello Witherspoon (concussion) are expected to play against the Los Angeles Rams, according to a report from Ian Rapoport of NFL Network. Another cornerback, Richard Sherman (calf), is expected to be a game-time decision.

All four players were listed as questionable on Friday's injury report. The only other player listed with the same status is wide receiver Trent Taylor (back).

Head coach Kyle Shanahan reported on Friday morning that wide receiver Dante Pettis (knee) will not play. Cornerback Jimmie Ward (hamstring) was listed as doubtful.

The 49ers and Rams kick off at 1:25 p.m. from Levi's Stadium.