Until now, the 49ers have not been a favorite in any game this season. Earlier in the week, the Buccaneers were 2.5-point favorites to beat the 49ers.
RB Doug Martin (hamstring) has been ruled out for the Buccaneers. While that is good for the 49ers, San Francisco will be without Carlos Hyde (shoulder).
The 49ers have lost five-straight games and have allowed a 100-yard rusher in each of those game. The team enters their bye week following today's game.
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The 49ers and Buccaneers kick off today at 1:05 p.m.
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