Below are several statistics and notes from Sunday's game, which were provided by the 49ers Communications staff.
With The Win...
- The 49ers improved to 5-2 all-time against the Jaguars, including a 3-2 record on the road.
- San Francisco has won each of the previous 5 meetings between the two teams.
- Head coach Kyle Shanahan improved to 6-3 against the AFC South and 3-0 against Jacksonville.
49ers defense
- The 49ers defense has held opposing offenses without a 100-yd. individual rusher in 36-consecutive games dating back to Week 9 of 2021 [vs. Arz. (11/7/21)].
- San Francisco's 36-consecutive games without an opposing 100-yd. rusher marks the longest active streak in the NFL and the longest streak by an NFL team since the New Orleans Saints streak from 2017-2020 [50-consecutive games without an opposing 100-yd. individual rusher [at LAR (11/26/17) – at Atl. (12/6/20)].
- It is also tied for the 3rd-longest streak in the NFL since at least 2000.
MOST CONSECUTIVE GAMES WITHOUT AN OPPOSING 100-YD RUSHER, SINCE 2000
| Rank | TEAM | GAMES | Dates |
| 1. | New Orleans Saints | 50 | 11/26/2017 - 12/6/2020 |
| 2. | Baltimore Ravens | 39 | 12/17/2006 - 10/4/2009 |
| 3t. | San Francisco 49ers | 36 | 11/7/2021 – 11/12/23 |
| Minnesota Vikings | 36 | 11/18/2007-12/13/2009 | |
| San Francisco 49ers | 36 | 11/29/2009 – 12/19/2011 | |
| 5. | Pittsburgh Steelers | 32 | 12/20/2007 - 12/20/2009 |
- The 49ers defense registered 5.0 sacks on the day, marking the 2nd time this season that the team has registered 5.0-or-more sacks [5.0 sacks at Pit. (9/10/23)].
- The 49ers defense registered 4 takeaways on the day (2 INTs, 2 FRs), marking the 2nd time this season that the unit has registered 4-or-more takeaways [4 takeaways vs. Dal. (10/8/23)].
- The unit's 2 games with 4 takeaways are the most since the 2020 season [4 takeaways at NE (10/25/20); 4 takeaways at LAR (11/29/20)].
Brock Purdy
- QB Brock Purdy completed 19 of his 26 passing atts. for 296 yds. and 3 TDs with a career-high passer rating of 148.9.
- Purdy's 3 TD passes give him 15 on the season and 28 in his career. His 66-yd TD pass to TE George Kittle marked the longest of his career.
- In Purdy's first two seasons, he has registered 3 games with 3-or-more TD passes and a passer rating of 140.0-or-more, making him just the 2nd player in NFL history to have 3 such games in their first two seasons (HOF QB Kurt Warner – 1999).
Brandon Aiyuk
- WR Brandon Aiyuk hauled in 3 recepts. for 55 yds. and 1 TD on the day, giving him 3 TDs on the season and 21 in his career.
George Kittle
- TE George Kittle caught 3 passes for 116 yds. and 1 TD on the day, giving him 4 TDs on the season and 35 in his career.
- With 149 yds. vs. Cin. (10/29/23) and 116 yds. on the day, it marked the 2nd time in Kittle's career that he's registered 100-or-more rec. yds. in back-to-back games [181 yds. at Sea. (12/5/21); 151 yds. at Cin. (12/12/21)].
- Kittle's 66-yd. TD recept. marked his longest recept. of the season and his longest TD recept. since Week 14 of the 2018 season [85-yd. TD recept. vs. Den. (12/9/18)].
- With 116 rec. yds. on the day, Kittle now has 559 rec. yds. on the season. His 559 rec. yds. make him just the 4th TE in NFL history to record 500-or-more rec. yds. in each of the first 7 seasons of his career (TE Rob Gronkowski, NE; TE Keith Jackson, Mia.; HOF TE Ozzie Newsome, Cle.).
Deebo Samuel
- WR Deebo Samuel caught 4 passes for 30 yds. through the air to go along with 3 carries for 29 yds. and 1 TD on the ground.
- Samuel's 23-yd. rush TD marked his 2nd of the season and the 16th of his career.
Kyle Juszczyk
- FB Kyle Juszczyk caught 2 passes for 26 yds. and 1 TD.
- His TD recept. marked his 2nd of the season and the 16th of his career.
Javon Hargrave
- DL Javon Hargrave registered 4 tackles and 1.5 sacks of Jaguars QB Trevor Lawrence, giving him 4.5 on the season and 42.0 in his career.
Clelin Ferrell
- DL Clelin Ferrell registered 1 tackle and 1.0 sack of Lawrence, giving him 1.5 on the season and 11.5 in his career.
Arik Armstead
- DL Arik Armstead registered 3 tackles and a 0.5 sack of Lawrence.
- Armstead's 0.5 sack gives him 3.0 on the season and 31.5 in his career.
Nick Bosa and Chase Young
- DL Nick Bosa and DL Chase Young split a sack of Lawrence.
- Bosa also added 1.0 sack and forced a Lawrence fumble on his 0.5 sack, giving him his first FF of the season and the 9th of his career.
- Bosa's 1.5 sacks give him 4.5 on the season and 47.5 in his career, which passes former DL Dana Stubblefield for the 4th-most sacks in 49ers franchise history.
MOST CAREER SACKS, FRANCHISE HISTORY
| Rank | Player | Sacks |
| 1. | DL Bryant Young | 89.5 |
| 2. | DL Charles Haley | 66.5 |
| 3. | LB Ahmad Brooks | 51.5 |
| 4. | DL Nick Bosa | 47.5 |
| 5. | DL Dana Stubblefield | 46.5 |
Fred Warner
- LB Fred Warner tallied 7 tackles, 1 PD and 1 INT of Lawrence, marking his 3rd INT of the season and the 7th of his career.
Talanoa Hufanga
- S Talanoa Hufanga notched 7 tackles, 1 PD and 1 INT of Lawrence.
- Hufanga's INT marked his 3rd of the season and the 7th of his career.
Ambry Thomas
- CB Ambry Thomas tallied 3 tackles and a FF on the day, the first of his career.
Jake Moody
- K Jake Moody connected on both of his FGAs (39 and 35 yds.) and all 4 of his PATs.
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