Both injuries occurred during Monday's practice. The 49ers are in their third and final week of organized team activities. The team will hold a mandatory three-day minicamp next week.
With Trent Williams absent, Skule had been starting in practice. He looked to be the 49ers' top backup to Williams and Mike McGlinchey during the upcoming season.
Shon Coleman could become the top candidate to replace Skule. Coleman opted out of last season due to COVID concerns after missing the 2019 season due to a broken fibula and ankle injury. He has not appeared in a regular-season game since the 49ers traded for him on August 31, 2018.
RELATED
"He's been here a lot this offseason, and he's really looking good, just out in workouts, which we'll see once we get on the field," general manager John Lynch said of Coleman in May. "But Shon's doing a nice job. We're pleased with that."
Moore had been starting in place of Jaquiski Tartt, who is dealing with a toe injury. San Francisco signed veteran safety Tony Jefferson on Monday.
The 49ers had already lost backup running back Jeff Wilson Jr. to what has been described as a "substantial" torn meniscus. He may not return until November.
Players will hit the practice field again today at noon, with offensive coordinator Mike McDaniel and select players scheduled to speak with reporters after the session.
San Francisco made Skule a sixth-round draft pick out of Vanderbilt in 2019. He has appeared in 31 games with 12 starts in his two seasons. The 49ers made Moore a third-round pick out of Southern Miss in 2018. He has appeared in all 48 games over the past three seasons, starting 13.
Related News
More San Francisco 49ers News
-
49ers great Roger Craig named 2026 Hall of Fame finalist
San Francisco 49ers legend Roger Craig took a significant step toward football immortality on Wednesday. The former NFL running back was named one of five finalists for the Pro Football Hall of Fame Class of 2026, joining senior finalists Ken Anderson and L.C. Greenwood, coach... -
The Stat No One's Talking About That Could Define the 49ers' 2025 Season
A lot has been written about the outstanding performance of San Francisco's coaching staff this year. Head coach Kyle Shanahan deserves all the praise for the work he's done with the offense and the overall team chemistry. Defensive coordinator Robert Saleh, of course, is... -
49ers overlook size concerns, add skilled receiver in The Athletic's 2026 NFL mock draft
The San Francisco 49ers could be in the market for a first-round wide receiver when the 2026 NFL Draft arrives. Brandon Aiyuk's future remains uncertain, and many around the league believe the veteran wideout has likely played his final snap for the 49ers—even after signing a... -
Schefter highlights 49ers RB Christian McCaffrey's historic 2025 season
San Francisco 49ers running back Christian McCaffrey is putting together a season for the history books. While he's averaging a career-low 3.6 yards per carry, his versatility as a playmaker in both the running and passing game makes him one of quarterback Brock Purdy's most...