The San Francisco 49ers finished their Week 16 "Monday Night Football" contest with a 48-27 win over the Indianapolis Colts at Lucas Oil Stadium.
49ers Light Up ‘MNF’ Win vs. Colts; 5 Takeaways from #SFvsIND
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Recap: Brock Purdy sets career touchdown mark while leading 49ers to 48-27 win in Indianapolis
By Kirk Larrabee
Dec 22, 2025
The San Francisco 49ers may not be playing defense at the level they've played in the past as they approach the postseason, but their offense certainly appears to be peaking at the right time.
The Indianapolis Colts had no answers for the 49ers' offense on Monday night, as...
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