Five 49ers players to keep an eye on in prime-time Week 16 game vs. Colts

The 49ers have been grinding it out this season.Through 14 games, San Francisco scored a league-high 139 points on drives that lasted 10 or more plays. It’s not the ideal situation for coach Kyle Shanahan, but he is learning to embrace this style of offense.“We might not have quite the same speed we’ve had other years,” Shanahan said this week on “49ers Game Plan.” “So I don’t think we have as many long plays, as many explosives, as we’ve had in years past. But whatever we’ve lost with that, I think we replace with more consistency.“I think we got some really good football players who know how to move the chains, who know how to stay on the field, and know how to get in the end zone.”The 49ers (10-4) enter their game Monday night against the Indianapolis Colts on a four-game win streak. They remain in the mix for the top spot in the NFC West and the No. 1 seed in the NFC playoffs.They will need to run the ball effectively and find a way to slow down the top rusher in the NFL in order to keep pace in the playoff picture.Here are five 49ers who must step up in order for San Francisco to...