The 49ers left State Farm Stadium with a seemingly lopsided 41-22 win over the Arizona Cardinals on Sunday, but their PFF grades show how much the home team was able to move the ball. The most obvious assist for the 49ers was the Cardinals’ franchise record-setting 17 penalties for 130 yards, which negated a 200-plus-yard differential between the two teams. The 49ers moved the ball 281 yards, while the Cardinals racked up 488 yards of offense. Defensive coordinator Robert Saleh put together a successful plan to stop the Cardinals’ ground game and allow only 36 rushing yards, but Arizona quarterback Jacoby Brissett completed a whopping 47 of his 57 total pass attempts for 452 yards with two touchdowns, two interceptions and a 96.8 passer rating. San Francisco coach Kyle Shanahan told reporters Monday that he was pleased with the defense’s performance, especially considering defensive end Robert Beal left the game after only seven defensive snaps, and linebacker Tatum Bethune missed nearly three quarters of the contest with what was determined after the game to be a high ankle sprain.“I was really proud of our defense,” Shanahan said via...
How PFF graded QB Brock Purdy, 49ers in blowout Week 11 win vs. Cardinals
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49ers vs. Cardinals PFF grades: Best and worst from the game, plus snap counts
49ers vs. Cardinals PFF grades: Best and worst from the game, plus snap counts
By David Bonilla
Nov 17, 2025
The San Francisco 49ers improved their record to 7-4 after a 41-22 win against the Arizona Cardinals in Week 11. Today, Pro Football Focus released its grades and snap counts from the game. Which Niners stood out, and who needs more work?
Highest-graded 49ers: Offense
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