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Brandon Aiyuk won’t have his 21-day practice window opened this week

Published Nov 4, 2025 at 1:00 PM
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Brandon Aiyuk is not ready to return yet. Almost two weeks after Kyle Shanahan said the star wide receiver was close to having his 21-day practice window opened, the 49ers coach said it won't be this week.Aiyuk remains on the reserve/physically unable to perform list as he continues to work his way back from ACL and MCL tears in his knee. He was injured Oct. 20, 2024, in a game against the Chiefs.The 49ers continue to say Aiyuk is "making progress" in his rehab, but more than a year after his injury, Aiyuk still is not back on the practice field.The 49ers off week is Week 14.Aiyuk had back-to-back 1,000-yard seasons in 2022 and 2023 before playing only seven games last season. He finished 2024 with 25 catches for 374 yards.

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