The San Francisco 49ers suffered another major injury and didn't have enough to overcome those issues in a Week 6 loss to the Tampa Bay Buccaneers.
49ers vs. Buccaneers highlights: San Francisco outgunned in NFL Week 6 game
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49ers vs. Buccaneers in Week 6: How to watch, stream, and listen, plus odds
By Site Staff
Oct 8, 2025
The San Francisco 49ers hit the road for the second consecutive week to take on the Tampa Bay Buccaneers at Raymond James Stadium. This matchup marks the 29th all-time meeting between the two teams, with the 49ers leading the series 21-7 and aiming to improve to 8-4 on the road...
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