Niners quarterback Brock Purdy's return from a toe injury lasted only one week. Purdy has officially been ruled out for San Francisco's Thursday night tilt against the Rams. Mac Jones will start in his place.
Niners QB Brock Purdy (toe) out Thursday night vs. Rams
Published Oct 1, 2025 at 1:20 PM
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49ers vs. Rams final injury report: Purdy, Pearsall, Jennings ruled out for TNF
By David Bonilla
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The San Francisco 49ers are preparing for their Week 5 contest against the Los Angeles Rams on Thursday at SoFi Stadium in Inglewood, California. Both teams have released their official injury reports, which are provided below.
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