What we learned as Brock Purdy, 49ers earn nail-biting opening win over Seahawks

What to Know Programming note: Immediately after the Week 1 game ends, watch “49ers Postgame Live” on NBC Sports Bay Area or stream the show in the NBC Sports app for full reaction, analysis and interviews. The 49ers started the 2025 NFL season 1-0 after a 17-13 win over their NFC West rival Seattle Seahawks on Sunday at Lumen Field. Quarterback Brock Purdy completed 26 of 35 passes for 277 yards with two touchdowns, two interceptions and a 92.2 passer rating. Running back Christian McCaffrey, who popped up on the 49ers’ injury report this week, started the game and finished with 22 carries for 69 rushing yards to go with 73 receiving yards on nine receptions. Kicker Jake Moody had another up-and-down game, making one of his three field-goal attempts. He missed from 27 yards, made a 32-yarder and his 36-yard attempt was blocked. Read below for all the game highlights, news, analysis and postgame press conferences from Lumen Field in Seattle: