On Thursday, just three days before the 49ers' season opener against the Seattle Seahawks, Christian McCaffrey popped up on the 49ers' injury report with a calf injury.
Christian McCaffrey leaves 49ers practice with troubling leg injury
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49ers vs. Seahawks injury report: Christian McCaffrey limited with calf issue
By David Bonilla
Sep 4, 2025
The San Francisco 49ers are preparing for their Week 1 contest against the Seattle Seahawks on Sunday at Lumen Field in Seattle, Washington.
Wide receiver Jordan Watkins (ankle) and defensive end Yetur Gross-Matos (knee) were the only active roster players to miss Wednesday's...
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