Here's everything to know about the 49ers' 2025 schedule, which features five prime-time games.
San Francisco 49ers release 17-game schedule: Takeaways, key stretch and predictions
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San Francisco 49ers' Full 2025 Schedule Revealed
By David Bonilla
May 14, 2025
The NFL unveiled its full 272-game schedule for the 2025 regular season on Wednesday at 5:00 p.m. PT. The action begins with NFL Kickoff Weekend on Thursday, September 4, and will culminate with Super Bowl LX on February 8, 2026, at Levi's Stadium in Santa Clara,...
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