49ers injury report: Guerendo foot sprain jeopardizes status vs. Rams

The 49ers might have to reach a little further down their depth chart to find another starting running back. Rookie running back Isaac Guerendo sustained a foot sprain in the 49ers' 38-13 victory over the Chicago Bears on Sunday, and his availability to face the Los Angeles Rams on Thursday night appears to be in question. "We'll evaluate him over the next few days to see if he's got a shot," 49ers coach Kyle Shanahan said Monday on a conference call with Bay Area reporters. Guerendo rushed for 78 yards and two touchdowns on 15 carries while catching two passes for 50 yards against the Bears. Guerendo gets his second score pic.twitter.com/ONNYRYqkId— 49ers on NBCS (@NBCS49ers) December 8, 2024 Guerendo earned his first NFL start after Christian McCaffrey (knee) and Jordan Mason (ankle) were placed on injured reserve last week. The 49ers previously lost running back Elijah Mitchell for the 2024 NFL season due to a severe hamstring injury during training camp. If Guerendo is unable to play on Thursday, the 49ers will turn to Patrick Taylor Jr., a four-year NFL veteran, as the lead back. "If Isaac can't go, it will be his opportunity," Shanahan said of Taylor. "If you saw him run...