The San Francisco 49ers have made the following roster moves ahead of tonight's Week 10 home game against the Los Angeles Rams.
WR Mohamed Sanu and S Tavon Wilson have been placed on injured reserve
S Tony Jefferson has been activated from the practice squad
The 49ers already ruled Sanu and Wilson out for Week 10. Sanu is dealing with a knee injury while Wilson is dealing with a foot injury. Safety Jimmie Ward (quadricep) was listed as "questionable" for tonight's game.
San Francisco enters tonight's game with a 3-5 record while Los Angeles is 7-2. Kickoff between the two teams is scheduled for 5:15 p.m. PT from Levi's Stadium. The Rams are currently favored by 3.5 points.
The two teams will announce their inactive players 90 minutes ahead of kickoff.
How the 49ers can mirror the Rams' success — even in a salary cap crunch
By Bob Heyrman
Mar 8
The Los Angeles Rams have become one of the most fascinating roster-building case studies in the modern NFL. For years, the narrative around the organization has been simple: aggressive trades, limited high-end draft capital, and a looming salary cap crunch. Yet despite those...
49ers face tougher NFC West as Rams land All-Pro CB
By David Bonilla
Mar 4
The San Francisco 49ers were already bracing for another demanding NFC West race after sharing the division with two playoff teams from this past season — including the defending Super Bowl champion Seattle Seahawks. With the Seahawks and Los Angeles Rams both projected to...
49ers NFL Combine Watch: Defensive Backs and Tight Ends Risers and Fallers
By Wayne "Breezie" Brown
Feb 28
The 2026 NFL Scouting Combine continued Thursday with defensive backs and tight ends taking the field, and several performances could directly impact the San Francisco 49ers' draft plans.
With speed, versatility, and matchup flexibility becoming priorities across the league,...
49ers NFL Combine Watch: Offensive Line Risers and Fallers Shake Up Draft Boards
By Wayne "Breezie" Brown
Mar 2
Day 4 of the 2026 NFL Scouting Combine belonged to the big men in the trenches, and several offensive linemen used the spotlight to shift their draft stock dramatically. For teams like the San Francisco 49ers — who continue searching for long-term stability along the...
